this study was done to determine whether high or low dose of anti-snake venom (asv) is better in coagulopathy in victims of envenoming by vipers. this retrospective study was conducted on the 154 patients (mean age ± sd, range) of viper snake bites who were referred to the emergency ward of razi hospital, ahvaz, iran over 2 years period (2004 - 2006). according to the treatment dosage the patie...

Snakebites can present local or systemic envenomation, while neurotoxicity and respiratory paralysis are the main cause of death. The mainstay of management is anti-snake venom (ASV), which is highly effective, but liable to cause severe adverse reactions including anaphylaxis. The types of adverse reaction to polyvalent anti-snake venom have not been previously studied in Bangladesh. In this p...

Many active secretions produced by animals have been employed in the development of new drugs to treat diseases such as hypertension and cancer. Snake venom toxins contributed significantly to the treatment of many medical conditions. Venomous snakes have a bad reputation and rightly so because of their often deadly bites. But what makes a snake’s bite so deadly is the venom. Of the 3000 snake ...

all desalination methods which are currently used have limitations. a newly designed instrument by zare a.m. was tested and compared with currently used method in razi vaccine and serum research institute(rvsri). samples of anti snake venom for desalination was provided by department of anti-serum, rvsri. parameters included in this study were time and water consumption during desalination proc...

Snake venom is a complex mixture of proteins, peptides, enzymes, carbohydrates, and minerals. They contain a variety of chemicals with pharmacological and toxicological properties. The innate immune system is the first line of defense against toxins and microbes. Antibacterial and anticancer proteins produced by snake venom have recently attracted significant attention due to their relevance to...

The Bridelia ferruginea plant as anti-snake venom activity against the venom of a clinically important snake, Naja nigricollis was investigated. The Bridelia ferruginea leaves were dried and extracted with ethanol and bioactive compounds such as tannins alkaloids,saponnin,flavonoids,steroids,terpenoids were determined by standard method. The effect of the extract on some selected enzymes activi...

Snake bite was known as one of the most important public health concerns world wild. Respiratory and cardiac problems and destruction of endothelium system occurs as a result of snake bite. Some proteins and peptides in snake venom have potential for drug discovery studies. According to the important role of cell adhesion and angiogenesis in cancer development, identification of new therapeutic...

Snake venom toxins are responsible for causing severe pathology and toxicity following envenomation including necrosis, apoptosis, neurotoxicity, myotoxicity, cardiotoxicity, profuse hemorrhage, and disruption of blood homeostasis. Clinically, snake venom toxins therefore represent a significant hazard to snakebite victims which underscores the need to produce more efficient anti-venom. Some sn...

Many active secretions produced by animals have been employed in the development of new drugs to treat diseases such as hypertension and cancer. Snake venom toxins contributed significantly to the treatment of many medical conditions. There are many published studies describing and elucidating the anti-cancer potential of snake venom. Cancer therapy is one of the main areas for the use of prote...

Snake bite is an important and serious global health issue. Till date anti snake venom serum is the only therapeutic remedy available for treating the snake bite victims. Infusion of ASV may lead to adverse reactions ranging from pruritus, urticaria to potentially fatal anaphylaxis. The development of ASV is also a costly and time consuming process requiring ideal storage conditions. Though Ant...